Louisville Cancer Treatment

The fight against cancer is one of the most daunting challenges confronting our health care system today. And nowhere in the United States is that battle raging more fiercely than right here in Kentucky. The state leads the nation in the number of people stricken by the disease, and in the number of cancer-related deaths.

For the past 30 years, UofL James Graham Brown Cancer Center has been working hard to change this through state-of-the-art clinical care, research, education and outreach programs. 

Patients newly diagnosed with cancer often experience tremendous anxiety about the many treatment options available. It often is difficult to navigate through a confusing maze of specialists and advice. If you are searching for a cancer expert, have been referred to a cancer expert at UofL Physicians or UofL Brown Cancer Center, or simply want to know where to get started, learn more at or call 502-562-HOPE (4673).

UofL Physicians includes many cancer experts across several specialties with different areas of expertise who treat adults at UofL James Graham Brown Cancer Center and children at UofL Physicians – Pediatric Cancer and Blood Disorders. We have a unified approach to cancer care, with multidisciplinary teams of physicians who work together to guide each patient through diagnosis, treatment and recovery. Our teams of cancer experts have an unparalleled depth and breadth of experience. 

Using this team-focused approach, our treatment plans reflect the combined expertise of many physicians -- surgical oncologists, medical oncologists, radiologists, radiation oncologists and pathologists, as well as psychologists, nutritionists and physical therapists. This approach also ensures that patients who need several different therapies to treat their cancer will receive the ideal combination.

We recognize that each patient is unique and each type of cancer is different -- the best treatment for one patient may not be right for another. Thus, we develop a treatment plan tailored for each patient. But the bottom line for all the cancer experts who are part of UofL Physicians is that we treat more than our patients’ cancers -- we care for the patient as a whole person.

Academic Comprehensive Cancer Program

In 2015, this Commission granted the UofL James Graham Brown Cancer Center their Outstanding Achievement Award, designed to recognize cancer programs that strive for excellence in demonstrating compliance with the Commission on Cancer’s standards and are committed to ensuring high-quality cancer care.  Only a small number of Academic Comprehensive Cancer Programs are accredited in the U.S. and an even smaller number received the Commission on Cancer’s Outstanding Achievement Award. 

The Academic Difference

At UofL James Graham Brown Cancer Center, we believe knowledge comes from questioning the status quo, discovering more about disease and using that knowledge to improve the health of our community. Our physicians are also teachers and researchers at the University of Louisville School of Medicine and are involved in the research and development of new treatments and cures for cancer. This means patients receive the most advanced and appropriate treatment even for complex or rare conditions. 

Since opening in 1981, UofL James Graham Brown Cancer Center has become home to some of the best scientists and physicians anywhere – delivering many exciting breakthroughs and the highest level clinical care. We provide and develop the most effective approaches to the prevention, diagnosis and treatment of cancer.

Our clinical programs offer patients the latest types of cancer treatments, state-of-the-art multidisciplinary care and, as an academic medical center at the forefront of medical research, access to innovative cancer trials.

With our rapid growth, especially over the past decade, we have become a nationally preeminent academic cancer center.  And through it all, we have kept our original goals at the heart of everything we do to:

  • Deliver the latest in medical advances to our patients, with compassion and respect
  • Raise the standard of cancer care in our region 
  • Generate new knowledge that helps us not just cure cancer in patients today, but prevent it in the next generation
  • Address the prevalence and impact of cancer on Kentuckians through outreach and prevention programs

Cancer must become a thing of the past. We at the UofL Brown Cancer Center are determined to make that happen.

Main Treatment Options

All methods depend on the type and stage of cancer or tumors.

  • Surgery – Removal of cancer or tumor. 
  • Radiation therapy - Treat small or early-stage tumors or used after surgery
  • Chemotherapy - Shrink the cancer before surgery or radiation
  • Targeted therapies - Tumor growth factors are hormone-like substances that occur naturally in the body and cause cell growth. Drugs that bind these substances or their partners on the cancer cell surface can inhibit tumor growth
  • Immunotherapy - Immunotherapy is a type of medication, usually infused into a vein, which helps your own immune system attack the cancer cells and destroy them.
  • Stem Cell Trasnplant - Use high doses of chemotherapy or radiation therapy to condition the body and then healthy stem cells then are given intravenously to stimulate new bone marrow growth
  • Transplant - entire organ is removed and replaced with a healthy donated organ.

UofL Brown Cancer Center has one goal - to END cancer.

This commitment involves conducting clinical trials with the goal of helping patients live longer, healthier lives. Through clinical studies, researchers can better understand how to diagnose, treat and prevent diseases or conditions. Any time you or a loved one needs treatment for cancer, clinical trials are an option to think about. Through the clinical trials at UofL Brown Cancer Center, doctors find new ways to improve treatments and quality of life for people with cancer.

Patients have access to new treatments, sometimes those that are not available anywhere else. Trials are available for all stages of cancer. It is a myth that clinical trials are only for people who have advanced cancer that is not responding to any other treatment; our clinical trial program features trials for all stages of disease.

Our researchers and physicians design cancer trials to test new ways to treat cancer, find and diagnose cancer, prevent cancer and manage symptoms of cancer and side effects from treatment.

To learn more about active clinical trials at UofL Brown Cancer Center, visit or call 502-562-HOPE (4673).

With our pioneering research at the University of Louisville, the UofL Brown Cancer Center gives patients their best chance to beat cancer.

Some of the greatest minds in cancer research are right here in Louisville at the University of Louisville's Brown Cancer Center. With the support of the UofL Health Sciences Center we have fostered the emergence of a leading Cancer Center making critical contributions to clinical care in the region and, through pioneering research, to cancer patients throughout the world. Much of the research that has been performed in our laboratories over the past 15 years includes clinical trials in humans, where new cancer drugs and diagnostics are being tested.

Importantly, we were and continue to be a key center for the global testing of several new drugs that activate your body's own immune system against cancer. These immunotherapies are resulting in prolonged survival of our patients who are participating in clinical trials and, as leaders in the field, we have incorporated their use in all of our cancer-specific multidisciplinary clinics.

Our specialists collaborate with other cancer experts – in different research areas and with the world's leading cancer doctors. Bright students and trainees contribute further to our dynamic research environment. Discoveries are fueled by vast research support and resources. Importantly, tomorrow's medicine is available to our patients first with our research efforts working in parallel to fight cancer through prevention, early diagnosis, effective therapies and scientific breakthroughs.

To find out more about our Cancer Research programs, visit


Physicians in this practice may not see patients at all locations listed below. For details, please call the appointment line for the location you are interested in visiting.

To learn more, please contact the following:

Offices and Clinics

  • UofL James Graham Brown Cancer Center
    529 S. Jackson St.

    Louisville, 40202
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  • UofL James Graham Brown Cancer Center (Medical Oncology)
    529 S. Jackson St.

    Louisville, 40202
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  • UofL Physicians - Surgical Oncology - Downtown
    401 E. Chestnut St.
    Suite 710
    Louisville, 40202
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  • UofL Physicians Surgery at Norton Medical Plaza - East End
    4950 Norton Healthcare Blvd.
    Suite 200
    Louisville, 40241
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  • UofL James Graham Brown Cancer Center (Radiation Oncology)
    529 S. Jackson St.
    Louisville, 40202
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  • UofL James Graham Brown Cancer Center (Gynecologic Oncology)
    529 S. Jackson St.
    Louisville, 40202
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  • UofL Physicians Gynecologic Oncology at Springs Medical Center
    6420 Dutchmans Parkway
    Suite 190
    Louisville, Kentucky 40205
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Hospital Affiliations

  • University of Louisville Hospital
  • James Graham Brown Cancer Center

Next Steps

For more information or to make an appointment,
call 502-588-6000